A STUDY OF ACETYLCHOLINESTERASE IN THE COCHLEA

Abstract

By Koelle's method for histochemical detection of Acetyl-Cholinesterase (ChE), we studied the localization of ChE in the cochlea, and following conclusions were made. In this method, copper sulfide deposit was demonstrated by the activity of ChE.
1) A greater concentration of copper sulfide was seen in the inner haircells than in the outer haircells.
2) The copper sulfide deposit was remarkable in the inner and outer haircells, specially at the base of the individual cells.
3) The copper sulfide deposit was remarkable in Lamina perforata, where the nerve fibers appear from the bone
4) Stria vascularis also showed minimal copper sulfide deposit.