HISTOLOGICAL STUDY ON THE PREVENTION OF MECHANISM OF OSSIFICATION FOLLOWING THE FENESTRATION OPERATION

Abstract

We Performed the Histological Studies for the pur pose of prevention of fenestra that closeing by ossification, fallowing to the fenestration operation of labirinth.
(1) On the normal rabbits, after 10th days the fenestra showed the States of fibrous inflammation, On the 30th days we found the periosteal assification is developping about 50th days, the fenestra is closeing by bone tissue and similarlyed bone tissue after 90th days, the fenestra showed ossific close due to the new bone.
(2) These rabbits which were injected Cortison, showed faint fibrous reaction, after 30 th days the fenestra is open and after the 50th_??_60th days, we could not found remarkable Exchanges in ossification of new bone, Then treating of cortison locally, It has a rather preventive effect of claseing the fenestra due to new bone.
(3) The rabbits which were loosed out the salivary gland, after the 30 th day there was no periosteal ossification and on the 50th_??_65th days the calcium deposition of fenestra was supressed and claseing mechanism of ossification was delayed.
(4) The rabbits which were injected Parotine, showed the strong fibrous inflammation, associated with calcium deposition and fenestra claseing mechaniom due to newbone was promoting.
(5) Useing of the faint skin-grafting valve, It was found that bone regeneration of fenestra is supressed.