A CASE OF COLE-ENGMAN SYNDROME
1982 Volume 85 Issue 3 Pages 283-287
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1982 Volume 85 Issue 3 Pages 283-287
A case of Cole-Engman syndrome which is a rare and fatal genodermatosis, characterised by the triad of reticulated hyperpigmentation of the skin, nail dystrophy, and leukoplakia of the mucous membrane was reported.
The patient was 16-year-old who had shown reticulated skin pigmentation on the bilateral ear, the neck, and the anterior chest, and atrophy and deformation of the nails for 5 years. Last year, folds and ulcers of the tongue emerged associated with pancytopenia, splenomegaly and hyperhidrosis in the regions of palms and soles.
Unfortunately, there was no effective treatments for this disease.
