MALIGNANCY IN NASAL AND PARANASAL 'TRANSITIONAL' PAPILLOMA

Abstract

Twenty-six cases of nasal and paranasal 'transitional' papilloma seen at our clinic during last 10 years were reviewed. Four of these 26 cases had associated malignancy. One case of papilloma showed malignant change during following up period, whereas in the other 3 cases, the initial biopsy proved the existence of carcinoma.
It is considered that in two of these 4 cases carcinoma may arise from a previously benign papilloma, according to histopathologic criteria.
It can be concluded that 'transitional' papilloma, in the so-called cancer-prone age, showing bleeding and evidence of bone destruction in radiological findings, has higher risk of associated malignancy. More extensive operative procedure and careful follow-up examination are strongly recommeded for such cases.