Abstract
We present a case of post methicillin-resistant Staphylococcus aureus (MRSA) infectious acute glomerulonephritis following cervical esophagus cancer surgery. Despite the subject's MRSA infection being treated successfully by antibiotics infusion, continuous hemodilution, and direct hemoperfusion with a polymyxin-absorbed immobilized column, hematuria, proteinuria, and serum creatinine gradually increased. Kidney biopsy showed rapidly progressive glomerulonephritis. This clinical course and examination findings yielded a diagnosis of post-MRSA infectious acute glomerulonephritis. Symptoms were gradually alleviated by steroid administration.
Post-MRSA infectious acute glomerulonephritis, a new disease, typically presents as rapidly progressive glomerulonephritis with nephrosis. It usually develops after malignant tumor surgery and especially, after MRSA infection sepsis. This disease must therefore be considered in the differential diagnosis of subjects with postoperative MRSA infection who show elevated hematuria and proteinuria, and worsening renal function. If nephritis progresses despite antibiotic treatment, steroid administration should be considered.
