2013 Volume 106 Issue 9 Pages 769-775
We introduce evidence for the efficacy of allergen immunotherapy, including sub-cutaneous immunotherapy (SCIT) and sub-lingual immunotherapy (SLIT), which are used internationally now. There is not the exact methodology established methodology, but a lot of succesful case reports, so SCIT is still used in Japan. The effect is large enough by the proper SCIT method form its evidence including the meta-analysis data. However, judging from the care setting in Japan, various problems still need to be resolved. Therefore, the SLIT approach, which appears to be the more easy-to-adopt approach, has received much attention inotherco-untries. Comparison of these two currently used routes for immunotherapy is still much debated. There are a large number of patients and doctors that are willing to the safer SLIT in Japan. Practical use of SLIT for pollinosis caused by Japanese cedar pollen is expected to be introduced in 2014.