2015 Volume 108 Issue 7 Pages 555-559
Apocrine carcinomas are a rare condition. In this report, a case of an apocrine carcinoma (AC) of the inferior eyelid is described.
A 55-year-old male patient was examined for right exophthalmos without diplopia, oculomotor dysfunction, or vision and visual field disorders. A tumor was identified in the right nasal cavity, and on palpation, the right inferior eyelid was indurated, and there was no palpable lymphadenopathy in the cervical region. AC was diagnosed by biopsy and immunostaining for GCDFP-15. A tumorectomy and reconstructive surgery were performed. No additional treatment was performed because the tumor margin was pathologically negative. We initially followed the patient postoperatively, but the patient on his own accord declined further examination. After three years of absence, the patient returned to our facility with the chief complaint of right cervical swelling. A fine-needle aspirate of the cervical swelling showed an adenocarcinoma. Because this tumor was a recurrence, the patient underwent a right modified radical neck dissection (m-RND). After two years of follow-up, a left cervical swelling was identified. He underwent a left m-RND and received titanium silicate chemotherapy for 6 months. However, brain metastasis was diagnosed on contrast-computed tomography. Chemotherapy was planned, but he died before receiving treatment.