Long-term Observation of Three Cases of Large Vestibular Aqueduct Syndrome

Abstract

The large vestibular aqueduct syndrome is a congenital disease characterized by inner ear malformation. The major symptom of this disease is difficulty in hearing and dizziness. According to a previous study, the hearing level gradually became worse with head trauma or strenuous exercise. However, several cases, hearing deterioration was not associated with any obvious events. There are few reports of long-term observation of cases of large vestibular aqueduct syndrome. We diagnosed 10 cases of this disease at our hospital and were able to follow up 3 of these cases for over ten years. The aim of this study was to investigate the clinical symptoms, especially by healing study and to discuss the characteristics of this disease by long-term observation.
As results, the cases with repeated and acute decreas in hearing level were not induced head trauma. The hearing level in most cases decreased gradually during the long-term observation, even though it recovered each time with acute medications.