2017 Volume 110 Issue 7 Pages 455-460
Patients with abnormal eye movements and dizziness are often encountered at the department of otolaryngology.
We report on 2 patients with dizziness who were referred to our otolaryngology department for examination, and were finally diagnosed as having paraneoplastic neurological syndrome (PNS).
In cases with abnormal eye movements, attention should be paid to the neurologic symptoms. PNS should be considered in the differential diagnosis, as it represents an important clue to the presence of an underlying malignant tumor.
It is necessary to perform whole-body CT or PET-CT, and tests for tumor markers and anti-neuronal autoantibodies. Since the neurologic symptoms often precede the discovery of the tumor and the initial tests for anti-neuronal autoantibodies could be negative, it is important to repeat these screening tests.
