2023 Volume 116 Issue 8 Pages 775-781
Sebaceous gland carcinoma is a rare but highly invasive tumor that usually occurs on the eyelids, face, neck, and trunk in patients over 60 years of age.
Herein, we report the case of a 71-year-old man who presented with a mass lesion of the right lower eyelid and right preauricular region. Histopathological examination revealed the diagnosis of sebaceous carcinoma with lymph node metastasis. After resection and reconstruction of the right lower eyelid tumor, we performed lobectomy of the right parotid gland with right neck dissection and postoperative irradiation for the right lower eyelid and right whole neck, and the patient is doing well.
Resection of the primary tumor is recommended for the treatment for sebaceous gland carcinoma, but there is still a lack of evidence and no clear recommendation in regard to the extent of lymph node dissection. Lymphatic flow from the lower eyelid differs between the inner and outer halves: the flow from the inner half is via the submandibular region, while that from the outer half is via the parotid region into the neck. Radiation has been reported to be effective. The treatment strategy should be determined by considering the extent of neck dissection based on the location of the primary tumor and adjuvant postoperative irradiation based on the degree of progression.
