2023 Volume 116 Issue 8 Pages 797-803
Primary thyroid malignant lymphoma (PTL) is a rare disease that accounts for 1%–5% of all thyroid malignancies. PTL is classified as a low-grade mucosa-associated lymphoid tissue (MALT) lymphoma or intermediate-grade diffuse large B-cell lymphoma (DLBCL). We report a case of MALT lymphoma of the thyroid gland that was diagnosed and treated by completion total thyroidectomy.
The patient was a 54-year-old man who has been under follow-up for Hashimoto’s disease and adenomatous goiter for 3 years. Regular ultrasonography showed gradual enlargement of the left lobe of the thyroid gland. A diagnosis of primary MALT lymphoma of the thyroid gland was made by completion total thyroidectomy. The low frequency of non-gastric primary MALT lymphoma makes large-scale clinical trials difficult, and optimal treatment has not yet been established.
The treatment options include radiation therapy, surgery, and chemotherapy, all of which have been reported to yield good outcomes be effective treatments. For localized-stage tumor, the main treatment is local radiation or surgery. In recent years, numerous reports have indicated that total thyroidectomy alone is effective for the treatment of localized-stage MALT lymphoma. Our case reported herein was successfully treated by total thyroidectomy without recurrence.
