A Case of Sigmoid Sinus Thrombosis Developing During Chemoradiotherapy for Locally Advanced External Auditory Squamous Cell Carcinoma

Abstract

We present a case of sigmoid sinus thrombosis that developed during chemoradiotherapy for locally advanced external auditory squamous cell carcinoma. The 78-year-old female patient underwent chemoradiotherapy (TPF-RT) for T3 left external auditory squamous cell carcinoma. She developed transit ischemic attack-like symptoms on day 30 of treatment. MRI revealed left sigmoid sinus thrombosis. Although thrombus formation predicted by irradiation has been reported, sigmoid sinus thrombosis is rare. It is important to check for D-dimer levels and perform MRI in patients who develop transit ischemic attack-like symptoms during CRT.