A Suspected Case of Wegener's Granulomatosis with Poor Eyesight, Hoarseness, Dysphagia and Hearing Loss

Abstract

We report a suspected case of Wegener's granulomatosis with poor eyesight, hoarseness, dysphagia and hearing loss. The variety of neurological symptoms made diagnosis difficult. But Wegener's granulomatosis was suspected because of the PR-3ANCA level. Symptoms were improved by steroid and cyclophosphamide administration, but the patient stopped cyclophosphomaide on his own initiative and hearing loss worsened thereaftered. Readministration of cyclophosphamide improved the hearing, but poor eyesight and recurrent nerve paralysis persisted.