Abstract
A case of Weber-Christian disease accompanied by a laryngeal ulcer was reported with a review of the literature. The patient was a 59-year-old female who complained of remittent fever, mucocutaneous nodules, swelling of the right cheek, and sore throat. Soon after the diagnosis of Weber-Christian disease was made by histological examination, labolatory findings, and the clinical picture, treatment with prednisolone was initiated. Responding to the steroid hormone, the laryngeal ulcer showed a tendency to heal, along with a striking clinical improvement of the other symptoms. Based on these findings, it is very likely that the laryngeal ulcer is a partial clinical symptom of Weber-Christian disease. Regarding the etiology of the disease, a special reference to the autoimmune disease is made.
