1983 Volume 76 Issue 11 Pages 3031-3039
A small tablet, Azulemic, is designed to release slowly water soluble Azulene when inserted into the labiogingival region. The clinical effects of Azulemic on pharyngitis and stomatitis were examined.
The method of this examination was a double-blind controlled trial in which Azulemic was compared with the standard drug.
Removing drop-outs and ruled-outs from a total number of 139, 130 cases were available for statistical analysis of the effects.
Compared with the standard drug, Azulemic showed superior effects in improving both subjective and objective symptoms, and in terms of global evaluation.
No side effects were observed.
Azulemic was regarded as an effective drug of long action for treatment of mucosal inflammation of the oral cavity.