Abstract
An immunologically normal 61-year-old man had bilateral resection of neck tumors and also a pharyngeal tumor during the past 4 years. A diagnosis of toxoplasmosis was made on the basis of the histological appearance of the resected tissue and a sudden rise of serum anti-toxoplasma titer. He was treated successfully with pyrimethamine and sulfadiazine. Toxoplasmosis should be considered in the differential diagnosis of neck and pharyngeal tumors. Recent reports have described disseminated toxoplasmosis in immunologically compromised hosts (mainly CNS toxoplasmosis) which appears to result from defects in cellular immunity that permit recrudescence of latent infection.
Therfore, CNS toxoplasmosis should be considered in the differential diagnosis of an evolving CNS syndrome in immunologically compromised hosts.
