Practica Oto-Rhino-Laryngologica
Online ISSN : 1884-4545
Print ISSN : 0032-6313
ISSN-L : 0032-6313
A Quantitative Evaluation of the Therapeutic Effect of Massive Dose Administration of Lysozyme on Chronic Sinusitis Using a Densitometer
Harumi SuzakiTakashi Futaki
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1983 Volume 76 Issue 4 Pages 1209-1215

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Abstract
X-ray opacity of the maxillary sinuses were evaluated using a densitometer in patients with chronic sinusitis whose subjective complaints and local findings of the nasal cavity were improved by massive dose administration of lysozyme (540mg/day).
X-ray films of the waters view were used for the following analysis. The density of the middle points within the orbita was used as the index of the orbital density. The density of the trisected points within the maxillary sinus was used as the index of the maxillary density. The remainder of these two indices was calculated to facilitate the comparison within a subject. The sets of data were compared between pre- and post-treatment. As a result of the densitometric estimation of the film, it was objectively shown that massive dose administration of lysozyme was significantly effective for chronic sinusitis.
Densitometric analysis of film minimizes the errors caused by radiographic conditions and subjective variations among the examiners. It is an excellent and useful method for quantitative evaluation of the therapeutic effect within a subject.
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© The Society of Practical Otolaryngology
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