1984 Volume 77 Issue 8 Pages 1681-1686
Tissue adhesion with highly concentrated human fibrinogen was used in 21 ear operations: seven cases of mastoid obliteration, ten canal wall reconstructions, two fascia grafts and three ossicular reconstructions.
Stabilization of grafted bone and fascial tissue makes subsequent operative manipulation easier and makes the survival of the grafted materials more certain. Thus, this tissue adhesive is very convenient and easy to use. Neither systemic nor local side effects were observed, and the postoperative clinical course was favorable. This human fibrin tissue adhesive can be recommended for use in middle ear surgery.