Hydrostatic Pressure in Experimentally Induced Endolymphatic Hydrops in the Guinea Pig

Abstract

With a servo-nulling pressure system the perilymphatic and endolymphatic pressures were measured continuously through the round window and basilar membranes 1-2.5 months after obliteration of the endolymphatic sac in 7 guinea pigs.
1) There was no significant statistical difference between the perilymphatic and endolymphatic pressures of the control ears.
2) The endolymphatic pressure was significantly higher (+0.78±0.32mm/Hg) than the perilymphatic pressure in the operated ears.