Abstract
Malignant hemangioendothelioma of the buccal region was diagnosed. Light microscopy with hematoxylin and eosin stain, reticulin stain, periodic acid Schiff stain and factor VIII-associated protein stain by the peroxidase antiperoxidase technique showed different characteristics in different areas of the same tumor, such as hemangioendotheliomatous and hemangiopericytomatous areas with fibrosis. It was thought that this tumor was an immature vascular tumor, and it was called a “cellular hemangioma”.