Abstract
A 36-year-male had two recurrent, large, elastic hard tumors, one was in the retroauricular region and the other in the inflaauricular region. Blood examination revealed an increase in eosinophils. The tumors were excised, and diagnosed as eosinophilic granuloma of the soft tissue by histological examination.
Electron microscopic investigation of the tumors revealed degeneration of eosinophils, such as the destruction of the granules, release of the tubular or spherical core from the granules, vacuolization, phagocytic vessicles containing amorphous necrotic debris, and enlargement of the perinuclear cysterna in the cytoplasm. The CharcotLeiden crystals were also found around the degenerated eosinophils, as a specific pathological finding.
