Abstract
Ketotifen 2mg in two doses a day was administered to 45 patients with nasal allergy for 4 consecutive weeks.
1) The rate of subjective improvement was 61.9% and of over-all improvement was 66.7%.
2) The three major symptoms of nasal allergy were reduced almost equally: 68.9% had fewer sneezing attacks, 72.1% less nasal discharge, 72.5% fewer attacks of nasal obstruction, and 60.0% less chronic nasal obstruction.
3) The onset of the therapeutic effect was within 2 weeks in 94.6% of all the improved cases. Patients with sneezing and nasal discharge noted greater improvement within 1 week than did those with nasal obstruction.
4) As side effects, drowsiness was noted by nine patients (20.0%), and two of them could not continue this drug.
5) Ketotifen was useful in 64.4% of this series for all types of nasal allergy.
