Local Injection of Bleomycin Emulsion in Therapy of Cystic Lymphangioma of the Head and Neck Region

Abstract

Three patients with the cystic lymphangioma of the head and neck region were treated with local injections of Bleomycin emulsion 1-3 times over the period of 1 month. In one patient, bleomycin injection was used following partial resection of the tumor. In the other 2 patients bleomycin emulsion was used as primary treatment. All 3 tumors decreased in size, and no severe complication was observed. Local injections of bleomycin emulsion may be indicated as the first choice for head and neck lymphangioma, since total removal and plastic reconstruction are technically difficult.