Juvenile Nasopharyngeal Angiofibroma

Abstract

Juvenile nasopharyngeal angiofibroma (JNA) is a relatively rare, benign, highly vascular tumor that almost exclusively affects adolescent males. This tumor is not limited to the nasopharynx and usually extends into the nose, paranasal sinuses, pterygomaxillary fossa, temporal fossa, cranium et al. Computed tomography (CT) and magnetic resonance imaging (MRI) are of great use in defining the extent of the tumor, bony destruction, sinus involvement and other extensions. Good results have been reported in the treatment of JNA with either surgical resection or radiation therapy. In general, most authors favor surgical resection, saving radiation for tumors with extensive intracranial invasions. Hormone therapy, chemotherapy, and arterial embolization have been used as auxiliary techniques, but generally have not been employed as primary treatment modalities. CT, MRI and selective angiography are important in the meticulous treatment planning and careful follow up in the management of this tumor.