成人喉頭乳頭腫ウイルスのDNA診断

杉田 麟也; 荻原 徹; 深本 克彦; 中井川 弘毅; 石 和久

doi:10.5631/jibirin.84.1097

DNA Evaluation for Human Papilloma Virus Infection in Adult Laryngeal Papilloma

Rinya Sugita, Tohru Ogiwara, Katsuhiko Fukamoto, Kouki Nakaigawa, Kazuhisa Ishi

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Keywords: laryngeal papilloma, human papilloma virus, in situ hybridization, dot blot hybridization, Southern blot hybridization

JOURNAL FREE ACCESS

1991 Volume 84 Issue 8 Pages 1097-1103

DOI https://doi.org/10.5631/jibirin.84.1097

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Abstract

Tissues from patients with adult-onset type laryngeal papilloma were examined for the presence of human papillomavirus (HPV).
The presence of HPV DNA was determined by in situ hybridization with biotin-labelled HPV DNA probes and by dot blot hybridization with ³²P-labelled HPV DNA probes.
Two cases of adult-onset type multiple laryngeal papilloma were positive for HPV-6, but a case of single laryngeal papilloma was negative for HPV.

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