Treatment of Otitis Media with Cefixime

Abstract

The clinical efficacy of Cefixime (CFIX) was evaluated in the treatment of otitis media. CFIX was administered orally to 35 patients with acute otitis media and to 12 patients with acute exacerbation of chronic otitis media.
A favorable clinical response was seen in 30 of the 35 patients in the former group (efficacy rate, 85.7%) and in 8 out of the 12 patients in the latter (66.7%).
Diarrhea occurred in 2 patients, but it ceased after discontinuation of the treatment.
This study indicates that CFIX is a drug of first choice in the treatment of acute otitis media.