Abstract
Drug therapy to suppress tinnitus is the easiest method for busy clinicians. However, there are many kinds of drugs and how to use of them is not clear. We tried to establish guidelines for choosing drugs based on the loudness of the tinnitus.
We prescribed alprazolam or bromazepam for tinnitus patients. Their efficacy is about 50-60% when used without regard to the loudness of tinnitus. However, when alprazolam was used for tinnitus of 0-5 dB SL and bromazepam for tinnitus of more than 6 dB SL, their efficacy was about 70-80%.
The anticonvulsant action of bromazepam is about twice that of alprazolam. We considered that very loud tinnitus is associated with higher seizure activity than less loud tinnitus, so it responds better to stronger anticonvulsant drugs.
Patients requesting treatment for not very loud tinnitus are generally nervous and have high MAS scores. Alprazolam is a stronger tranquilizer than bromazepam, and such patients respond well to alprazolam.
This medicinal treatment of tinnitus based on loudness showed good results.
