Practica Oto-Rhino-Laryngologica
Online ISSN : 1884-4545
Print ISSN : 0032-6313
ISSN-L : 0032-6313
Sclerodermoid Skin Metastasis to the Neck from an Undetermined Primary Site; A Case Report
Toru TakimotoMakoto Itoh
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1993 Volume 86 Issue 3 Pages 385-388

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Abstract
An 86-year-old man with a sclerodermoid lesion of the neck visited our outpatient clinic complaining of slight dyspnea. Histological examination revealed anaplastic infiltrating carcinoma with various degrees of cellularity, a loose stroma, and scattered signet ring cells that contained intracytoplasmic mucin and laterally displaced nuclei. Signet ring cells are most commonly seen in metastases of adenocarcinoma of the stomach, and occasionally in metastatic lesions from adenocarcinoma of the lung and breast. However, in our patient the primary cancer remains undetectable despite careful work-up and eight-month follow-up examinatlons.
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