Abstract
The incidence of deep neck infection has decreased since the development of antibiotic therapy. However, there are still some severe cases with serious complications, such as lethal necrotizing mediastinitis. A 51-year-old and a 54-year-old male patient with mediastinitis secondary to deep neck infection were treated in our department. They developed mediastinitis within a few days after the diagnosis of deep neck infection. They had no systemic disease, such as diabetes. They were treated successfully with early debridement and surgical drainage from both the neck and the mediastinum. When the diagnosis is established or suspected, prompt surgical drainage and washing with antibiotics are necessary in the management of deep neck infection.