1994 Volume 87 Issue 10 Pages 1363-1367
Olfactory neuroblastoma is an uncommon malignant tumor of neural crest origin arising from the olfactory epithelium. It was originally described by Berger in 1924, and since then many cases have been reported. But in Japan the disease is uncommon, and it is difficult to diagnose.
We recently treated a 42-year-old male with olfactory neuroblastoma invading the skull base. We performed cranio-facial surgery after radiation and chemotherapy. There has been no recurrence of the tumor more than 10 months after surgery.