Salivary Gland Tumors; Clinical Analysis of 96 Cases

Abstract

We reviewed our 11-year experience with 96 patients treated for salivary gland tumors originating in the parotid gland (72 patients, 75%), submandibular gland (11 patients, 11%), and minor salivary glands (13 patients, 14%). The most common histology was pleomorphic adenoma, 57% of the total (77% of the benign tumors). The distribution of patients according to the histology and the site of origin are summarized.
Survival in patients with malignant tumors differed significantly according to the histological grade and clinical stage. Postoperative irradiation was useful in the local control of tumors with a high grade of malignancy and suspicion of microscopic residual disease. Chemotherapy for unresectable or recurrent carcinomas had a poor response rate (33%) and short response duration (8 to 12 weeks).