Prophylactic Treatment of Pollinosis with Oxatomide; An Objective Evaluation

Abstract

In this objective evaluation of the efficacy of prophylactic treatment for Japanese cedar pollinosis during natural allergen exposure, oxatomide (60mg/day, per os) was administered during the spring of 1993. The prophylactic treatment group (n=10) received the medication from Jan. 11. The no treatment group (n=10) did not receive the medication. Total subjective symptom scores, blood eosinophil counts and the level of albumin in nasal secretions were examined and compared in two groups on Mar 12.
Three parameters in the prophylactic treatment group were lower than those in the no treatment group. The differences in subjective symptoms and blood eosinophil counts were significant. The effect of prophylactic treatment can be evaluated objectively.