Abstract
We report a case of teratocarcinosarcoma involving the right nasal cavity. The patient was a 55-year-old male, whose chief complaints were right nasal obstruction and bleeding. Histological, immunohistochemical and electron microscopic findings of the biopsied nasal tumor revealed an epithelial component of squamous cell carcinoma and mesenchymal components of myofibrosarcoma, chondrosarcoma and undifferentiated sarcoma with small nuclei. The patient was treated with intensive irradiation and chemotherapy, and a total maxillectomy. He has had no recurrence to the present.
Teratocarcinosarcoma, consisting of a malignant epithelial element and two malignant mesenchymal components, is exceptionally rare in the sinonasal tract with only 28 reported cases, including the present patient. Rapid growth and extensive local destruction are prominent features of this type of tumor, emphasizing the need for early diagnosis and prompt introduction of aggressive therapy.
