Abstract
A rare case of extramedullary plasmacytoma in the epipharynx and palatine tonsil is reported. A 63-year-old woman with left hearing loss due to otitis media with effusion was examined at our hospital. Physical examination and MRI showed mass lesions in her epipharynx and right palatine tonsil without cervical lymphadenopathy. Histological studies of biopsy specimens from both lesions showed extramedullary plasmacytoma. Immunohistological study revealed that tumor cells were positive for kappa chain of immunogloblin light chain, but negative for heavy chain. There were no abnormal findings in the serum immunoglobulin level, serum and urine protein levels, or bone marrow biopsy. Surgical resection of the tumors was performed followed by radiotherapy with a total dose of 60 Gy to the upper neck including the epipharynx and palatine tonsil. Post treatment, she has been free from disease for 15 months.
