Abstract
Basaloid squamous cell carcinoma (BSCC) is high grade, aggressive variant of squamous cell carcinoma with a predilection for the larynx, hypopharynx, and the base of the tongue. It is found in only 2-3% of cancers in the nasal cavity and paranasal sinuses within the head and neck region. BSCC originating in the paranasal sinuses has rarely been reported. Herein we report the third known case in Japan. An 85-year-old woman presented with a complaint of left nasal obstruction. On examination, obstruction of her left paranasal sinuses, nasal cavity and cervical lymph node metastasis were found. Radiotherapy and chemotherapy were performed, but the tumor size was unchanged and she died of rupture of aortic aneurysm. We suggest that radiotherapy and chemotherapy were somewhat effective in this case. It is important to observe patients closely after treatment because BSCC shows aggressive behavior.
