Abstract
Differences in the effects of steroid and isosorbide for acute low-tone sensorineural hearing loss (ALHL) were examined. The steroid group showed significant improvement compared to hearing levels after the same length of treatment in the isosorbide group. Since endolymphatic hydrops was considered the etiology, some ALHL patients progress to Meniere disease. However, isosorbide improves endolymphatic hydrops in ALHL patients. Our findings showed that ALHL also has etiologies other than an endolymphatic hydrops and that these also respond to steroid administration.