2013 Volume 136 Pages 145-149
In 2001, Hamano and others reported elevation levels of serum IgG4 in autoimmune pancreatitis patients who demonstrated lymphoplasmacytic infiltrates and sclerosis in the pancreas. IgG4-related disease is a recently recognized systemic syndrome characterized by various systemic disorders,mainly occuring in exocrine tissue. A pathological organizational diagnosis of IgG4-related disease is easily managed with biopsy of the mandibular gland. We report herein on our experience with three cases of IgG4-related disease.