2013 Volume 136 Pages 89-94
A case of olfactory neuroblastoma is reported herein. A 59-year-old man visited our hospital with right nasal drip and chronic cough in November 2001. An examination revealed a tumor in his right nasal cavity, the surface of which was smooth and dark white. The patient did not have any visual acuity difficulties and the cervical lymphnodes were not swollen. The patient underwent surgery for a nasal tumor in December 2001. Based on the pathological findings, we made a diagnosis of olfactory neuroblastoma with a clinical Kadish staging score of stage A.
The patient was treated with 57.6 Gy carbon-ion beam therapy, and became free from disease. Eight years later, a right upper neck metastasis was discovered with elevation of serum NSE levels. Subsequently, the tumor was removed completely with neck dissection.
The patient has been followed up periodically and to date no recurrence of the tumor has been observed. The measurement of the serum NSE level seemed to be useful for diagnosis of recurrence in patients with olfactory neuroblastomas.
