Practica oto-rhino-laryngologica. Suppl.
Online ISSN : 2185-1557
Print ISSN : 0912-1870
ISSN-L : 0912-1870
Effectiveness of Positron Emission Tomography-Computed Tomography in Evaluation of Superselective Intra-arterial Chemoradiotherapy in Patients with Advanced Maxillary and Upper Gingival Carcinomas
Haruo HirakawaYasuyuki NishiMakoto TadaTaisuke Watanabe
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JOURNAL OPEN ACCESS

2015 Volume 144 Pages 74-75

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Abstract

We have been applying superselective intra-arterial chemoradiotherapy (SIACRT) to advanced squamous cell carcinomas of the maxillary sinus and upper gingiva since 2009. We reported the outcomes of SIACRT in this journal recently. SIACRT is a promising therapy to preserve the patient’s quality of life both during and after the treatment, without sacrificing the cure rate. However, we cannot but use imaging to evaluate the SIACRT response, because visual observation of the lesion is difficult with the maxillary sinus not fenestrated in our therapeutic method. We use 18F-FDG-Positron emission tomography-computed tomography (PET/CT) to evaluate the SIACRT response. This report shows the PET/CT findings of the same patients we reported in this journal recently, before and after SIACRT. We also mention squamous cell carcinoma antigen (SCC) of the patients as a guide to the response evaluation. The 1st PET/CT around 3 months after SIACRT showed false positive in many of the cases. Another PET/CT 1–2 months later could evaluate the SIACRT response more correctly. SCC might help for the evaluation using PET/CT.

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© 2015 The Society of Practical Otolaryngology
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