2023 Volume 163 Pages 112-116
We investigated the data of 24 patients with carcinoma of the submandibular gland who were treated by radical surgery. The histological grade was low in 1 case (4%), intermediate in 13 cases (54%), and high in 10 cases (42%). Adenoid cystic carcinoma was the most common subtype (11 cases, 46%). The 5-year overall survival (OS) rates according to the c (clinical) T classification were: cT1, 100%; cT2: 48.6%; cT3, 52.0%; and cT4, 0% (3 years) (P = 0.049). The 5-year OS rates according to the cN classification were: N(–), 88.9%; and N(+), 23.1% (P = 0.005). The 5-year OS rates according to the histological grade were: low grade, 100% (2 years); intermediate grade, 83.1%; and high grade, 13.3% (P = 0.010). cN(+) and high malignancy grade were predictive of an unfavorable prognosis. These treatment outcomes in our study are slightly inferior to those reported previously. In addition, in all of the patients who died of the primary disease, the death was caused by distant metastases.
