Eosinophilic Granuloma in the Soft Tissue (Kimura's Disease)

Abstract

We report 11 patients with eosinophilic granuloma in the soft tissue or Kimura's disease.
The patients were 8 males and 3 females. The eosinophilic granuloma may occur not merely subcutaneously but also submucosaly in Kimura's disease because the granuloma was detected at the epipharyngeal opening of the auditory tube in one case of the disease with parotid tumor. There was a tendency in the recurrence of the disease to be delayed when the number of eosinophilic leukocytes in the peripheral circulation had been reduced to the normal range after treatment. In radiation therapy,20 Gy was enough to abolish or to reduce the size of granuloma and combination radiotherapy with steroids was more effective than simple irradiation to prevent recurrence.