Clinical Review of 82 Cases with Non-Hodgkin's Lymphoma
1991 Volume 1991 Issue Supplement42 Pages 188-194
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1991 Volume 1991 Issue Supplement42 Pages 188-194
We retrospectively made a clinical study of 82 cases of non-Hodgkin's lymphoma which we treated between 1975 and 1988.
The onset sites were Waldeyer'sring in 48 cases, the largest number, followed by cervical lymph node in 19 cases. By stage,32 cases stage II and 22 cases stage I, the sum of which acounted for 66%. LSG classification resulted in 5 cases of follicular lymphoma and 77 cases of diffuse lymphoma. Of these diffuse type cases, the most (44 cases) were large cell type and 11 cases pleomorphic cell type. The latter had a higher death ratio. A study of surface markers by using anti-B and-T lymphocyte sera showed 15 cases of B cell type,12 of T cell type and 1 of Null cell type. Stage I cases included more of B cell type and advanced cases comprised more of T cell type. As to therapy, of the stage I and 1E cases all of which survived, radiation therapy alone was performed in 14 and combined radiation therapy and chemotherapy in 7. Seventeen of the stage II and IIE cases, underwent combined therapy, one of which was a death case. In many of stage III and IV cases, the general condition treatment and that made it difficult to continue the treatment. Examination of 5year survival rates induced: stage I (n=22): 100%, stage II (n=32): 75.8%, stage III (n=9): 17.3%, and stage IV(n=19): 17.1%.
In conclusion, if a diagnosis has bee n made to a certain degree by otolaryngologic palpation and inspection and treatment started before making a histological or stage diagnosis, even non-Hodgkin's lymphoma can be treated as local disease, and the survival rate improved.
