A Clinical Study of Paranasal Sinus Mycosis

Abstract

A case of aspergillosis with the maxillary sinus cured by peroral antimycotic drug was reported.
A 71-year-old woman visited our clinic complaining of right nasal obstruction and purulent nasal discharge. A necrotic mass was found in the middle meatus of the right nasal cavity. A CT-scan revealed a large soft tissue mass occupying the right maxillary sinus extended through the medial wall to the nasal cavity. Biopsy specimens from the mass showed a characteristic picture of aspergillosis. Conservative treatment with oral administration of the antimycotic drug, fluconazole was carried out. The aspergillosis was cured within seven weeks.
Treatment with oral administration of fluconazole is recommended as the first choice of the paranasal sinus mycosis as well as follow-up treatment for the prevention of recurrence after surgery.
In addition to this case report,10 cases of primary fungal infections in the paranasal sinuses treated in Yamagata University Hospital during the 14 years from 1976 to 1991, have been reviewed.