1991 Volume 1991 Issue Supplement51 Pages 215-221
Autopsy findings in a case of nasal T cell lymphoma were reported. A 56-year-old male first developed bilateral nasal obstruction, and was operated as sinusitis in another hospital. Four months later, he developed spiking fever and severe crusting in the nasal cavity. He was treated as Wegener's granulomatosis with prednisolone and cyclophosphamide, but the treatment was not effective. Necrosis of hard palate was rapidly developed, the biopsy specimens from the palate showed proliferation of lymphoma cells. The lymphoma cells were considered to be T cell origin immunohistochemically. After receiving the diagnosis, he was treated with irradiation and VEMP therapy. However, he died from respiratory insufficiency 6 months after onset of spiking fever. The infiltration of lymphoma cells was observed in almost all organs at the autopsy.
