1992 Volume 1992 Issue Supplement53 Pages 56-65
The labyrinthine pathophysiology during the occurrence of aural vertigo was investigated by clinical observations and animal experiments. As a rule, irritative or paralytic nystagmus can be frequently observed during the vertiginous attack. In order to know the mechanism of nystagmus, a histochemical study of the vestibular sensory cells and autoradiographic study of the vestibular nuclei were performed for the model animals of the Meniere's attack. From the results, it was proved that the excitement of the affected side labyrinth and ipsilateral vestibular nucleus provoked irritative nystagmus. On the other hand, paralytic nystagmus was provoked by the paralysis of the affected side labyrinth and the excitement of the contralateral vestibular nucleus.
