Non-Specific Granuloma of the Larynx

A 20-Years Review of 129 Patients

Abstract

A retrospective review of 129 patients with non-specific laryngeal granuloma who visited to our clinic between 1971 and 1990 is presented. Eighty-two out of 128 cases were intubation granuloma,25 were contact granuloma and 22 were ideopathic. Females were predominant in intubation granuloma, while males predominated in contact and ideopathic granulama. There was no significant difference in age distribution among intubation, contact and ideopathic granulomas. Almost all cases had granulomas near the posterior glottis, but the granuloma was near the anterior commissure in two cases and below the glottis in one case. Surgical removal was performed for 70 patients; 14 with indirect laryngoscopy, one with laryngeal fiberscopy and 55 with endolaryngeal microsurgery. Recurrence occurred in 20% of intubation granulomas, in 46% of contact granulomas and in 36% of ideopathic granulomas. Thirty two patients were treated with conservative therapy, mainly voice therapy. In 24 of those cases, the granuloma disappeared. Only one case had recurrence of the granuloma after conservative therapy.