Practica oto-rhino-laryngologica. Suppl.
Online ISSN : 2185-1557
Print ISSN : 0912-1870
ISSN-L : 0912-1870
IgE Positivity Rate to Spring Pollens in Patients with Japanese Cedar Pollinosis
IgE Positivity Rate to Spring Pollens
Nobuo TakagiYukari MasudaRyo KawataFumikazu MizukoshiHiroshi TakenakaKenji DejimaKenji SaitoNoriko Kakisaki
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1995 Volume 1995 Issue Supplement76 Pages 42-46

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Abstract

Pollinosis caused by Japanese cedar is occurs most frequently in this country. Japanese cedar begins to release pollen in February or March every year. Many patients with Japanese cedar pollinosis are known to show allergic reaction to the pollen of some other plants.
Here in, we report the incidence of positive reaction of Japanese cedar po llinosis patients to tests for IgE antibody to pollen antigens derived from trees other than Japanese cedar.
In 120 established cases of Japanese cedar pollinosis, anti-Mountain j uniper antibody was measured. Antibodies to 4 other trees (Grayalder, White oak, Japanese beech and Walnut) were measured in 80 cases. A Pharmacia CAP system was employed to measure specific IgE.
The positive rate was 81.2% for Mountain Juniper,14.8% for Gray alder,9.9% for White oak,8.6% for American beech,7.4% for Walnut.
Using sera showing high antibody titers against Japanese cedar and Mountain juniper, a White cedar antigen absorption test was performed. Anti-Japanese cedar and anti-Mountain Juniper IgE titer was obtained by absorbing White cedar antigen in sera at a dilution rate from 1: 1.5 to 1: 60000. At high concentrations of antigen, dilution rate of 1: 1.5, both antigen titer decreased less than 50%. However, at dilution rates at 1: 12 to 1: 1200, only anti-Juniper antibody titers was suppressed. This indicates that some antigens differented, among Japanese cedar, Mountain Juniper and White oak.

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