Eosinophil Infiltration in Nasal Polyps

Abstract

Recently, the number of patients with allergic nasal polyps has been increasing, and this is associated with an increasing incidences of eosinophil infiltration in nasal polyps. We examined 33patients with nasal polyps and analyzed the histological type as well as the state of eosinophil and plasmocyte infiltration in the polyps. The results were edema type 70%, adenocystic type 24%, and fibrous type 6%. Eosinophil and plasmocyte infiltration were observed in 70% and 73% of the total, respectively. In comparison of 12 allergic nasal polyps to 12 non-allergic nasal polyps, eosinophil infiltration was increased in the allergic polyps. When an anti-allergic drug was administered to 5 patients with allergic nasal polyps for more than 3 months prior to surgical treatment, good postoperative results were obtained. However, the degree of eosinophil infiltration was nearly the same as that of patients who did not receive any anti-allergic drugs.