1995 Volume 1995 Issue Supplement83 Pages 90-94
Squamous cell carcinoma-related antigen (SCC antigen), which was purified from the tissue of liver metastasis from uterine cervical squamous cell carcinoma, is clinically available as a tumor marker for squamous cell carcinoma.
This is a case report of inverted papilloma of the nasal cavity diagnosed in a 56-year-old male with high serum SCC antigen level. CT-scan revealed a well circumscribed mass in the left nasal cavity. The tumor was difficult to detach at surgery because of synechia with the left middle turbinate, so it was completely resected including the left middle turbinate. The high serum SCC antigen level quickly declined to the normal level after surgery. Histopathological examination of the resected tumor showed typical features of inverted papilloma without malignancy. Immunohistological distribution of SCC antigen in the tissue of the resected tumor was observed by the strepto avidin-biotin peroxidase complex-method (SABC-method). SCC antigen immunoreactivity was diffusely present in the cytoplasm of tumor cells.
The findings suggest that SCC antigen is available as a tumor marker for inverted papilloma.
