1998 Volume 1998 Issue Supplement98 Pages 44-48
To evaluate the clinical efficacy of Tsumura Sairei-to in the treatment of chronic otitis media and cholesteatoma after a tympanoplasty, an open randamized trial study was performed on 12 patients. The efficacy rate on the ear drum and fascia was 66.7%, and the efficacy rate on the mastoid was also 66.7%. The efficacy rate against the overall subjective symptoms was 66.6% of the 12 patients significant effects were observed in five patients (41.7%), slight effects were observed in another five patients (41.7%), and no noticeable effects were observed in two patients (16.7%). The general efficacy rate for the 12 patients treated with Tsumura Sairei-to was 83.4%. No side effects were noted in any of the patients, so the general usefulness rate was also 83.4%. These results suggest that Tsumura Sairei-to is clinically effective as an oral therapy against chronic otitis media and cholesteatoma after a tympanoplasty.
